Journal of Woundcare Handbook

The professional's guide to wound product selection

Integra Meshed Dermal Regeneration Template

Integra LifeSciences


An advanced bilayer matrix for dermal regeneration. The dermal replacement layer, consisting of a porous three-dimensional matrix comprised of bovine tendon collagen and chondroitin-6-sulfphate, is designed to have a controlled porosity and defined degradation rate, and promotes wound healing in a single application. The temporary epidermal layer is made of synthetic polysiloxane (silicone). The semipermeable silicone membrane controls water vapour loss, provides a flexible adherent covering for the wound surface, and adds increased tear strength to the device. Can be used in conjunction with NPWT.


Post-excisional treatment of full-thickness and partial-thickness injuries where sufficient autograft is not available at the time of excision or not desirable due to the physiological condition of the patient. Also indicated for use in reconstruction of post-excisional, full-thickness defects of the integument, where there is, in the opinion of the treating surgeon, a potential benefit to the patient by improving the reconstructive outcome or decreasing their mortality/morbidity.


Hypersensitivity to bovine collagen, chondroitin sulfate derived from shark cartilage or silicone; clinically diagnosed infected wounds – if using with NPWT, any device-specific contraindications, such as exposed arteries, veins, organs, anastomotic sites or nerves; malignancy in wound; untreated osteomyelitis; untreated malnutrition; necrotic tissue; non-enteric/unexplored fistulas; sensitivity to silver (if silver dressings are used)


5×5cm, 10×12.5cm, 10×25cm, 20×25cm, not on Drug Tariff

More on: Cellular, acellular and matrix-like products